Has there ever been a show about a mixed-gender group of adult friends where there are no romantic entaglements within the group?

Feels like asking if there's a show where the main characters never eat together. Sex and food are sorta what we do. Like as a species. A show would have to be very limited in scope to leave one of those things out.

Dee and Charlie bang.

Mac bangs Dee and Dennis' mom.

Frank bangs Charlie's mom (a lot).

Frank, Charlie, and Dennis all bang the waitress.

Dennis tries to bang Mac's mom.

Frank and Mac both try to bang Dee and Dennis' Aunt Donna.

I think Frank bangs Dee and Dennis' cousin Gail the Snail

But all of these are one off bits rather than being part of a larger arc or plotline, so I think it still fits the spirit of the question.

Only Murders in the Building

I was going to say Spaced till I remembered Twist and Brian have their weird thing and he maybe slept with Marsha. Tim and Daisy never hook up tho, but they do pretend to be a couple for a bit to get the flat.

Black Books - Bernard does mention he once possibly might have slept with Fran but she made him forget, and then it never comes up again.

Power Rangers?

Maybe a group of aces?

Nice try, I thought of the A-team but there's no girls, there's some in later seasons but not really a major part.

That was my guess too, but I needed someone with more memory of the show to confirm

30 Rock. None of the core group ever get together. There's a little bit of sexual tension between jack and lemon but it's always clear that it will never go anywhere

Omg I forgot What We Do in the Shadows!!

B99 does the romance trope

Harry and D'Arcy dated for a few episodes (maybe only one or two, I don't recall clearly). There was a bit of teasing that Asta and Harry would be a thing at some point but thankfully that never materialized.

There were definitely romantic relationships with side characters - Sheriff Mike had a couple, obviously the mayor and his wife, Harry and the bird lady, Liz had a boyfriend (though he rarely appeared or was even mentioned), plus D'Arcy tried a few times to find love and Judy... had several flings?

Mac and the waitress do hand stuff.

Did you forget about Golden Girl pilot where they had a gay housekeeper? Mixed gender bam!!!

The advengers.